Search for clues that connect to the papers
You pick up the apple that mysteriously has a slice removed from it. You add the 1 (ONE) APPLE to your INVENTORY.

You figure you could squeeze this apple's juice out onto the TATTERED NOTE, light a match and check it for hidden messages, so you'll hold onto it.

There aren't really any other clues for finding the combination for that safe that you can see around.

Quickly put on a hat